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Unspecific binding of cRNA probe to plaques in two mouse models for Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is characterized by the pathological deposition of amyloid-β (Aβ) protein-containing plaques. Microglia and astrocytes are commonly attracted to the plaques by an unknown mechanism that may involve cell adhesion. One cell adhesion family of proteins, the cadherin...

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Detalles Bibliográficos
Autores principales: Schaarschuch, Anne, Redies, Christoph, Hertel, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159973/
https://www.ncbi.nlm.nih.gov/pubmed/27978824
http://dx.doi.org/10.1186/s12952-016-0065-9