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Aberrant CBFA2T3B gene promoter methylation in breast tumors

BACKGROUND: The CBFA2T3 locus located on the human chromosome region 16q24.3 is frequently deleted in breast tumors. CBFA2T3 gene expression levels are aberrant in breast tumor cell lines and the CBFA2T3B isoform is a potential tumor suppressor gene. In the absence of identified mutations to further...

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Detalles Bibliográficos
Autores principales: Bais, Anthony J, Gardner, Alison E, McKenzie, Olivia LD, Callen, David F, Sutherland, Grant R, Kremmidiotis, Gabriel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC516017/
https://www.ncbi.nlm.nih.gov/pubmed/15301688
http://dx.doi.org/10.1186/1476-4598-3-22