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Analysis of HIV-1 Vpr determinants responsible for cell growth arrest in Saccharomyces cerevisiae
BACKGROUND: The HIV-1 genome encodes a well-conserved accessory gene product, Vpr, that serves multiple functions in the retroviral life cycle, including the enhancement of viral replication in nondividing macrophages, the induction of G2 cell-cycle arrest, and the modulation of HIV-1-induced apopto...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC516023/ https://www.ncbi.nlm.nih.gov/pubmed/15312229 http://dx.doi.org/10.1186/1742-4690-1-21 |