Estimates of statistical significance for comparison of individual positions in multiple sequence alignments

BACKGROUND: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistically confident dissimilarities between (1) MSA position and a set of predicted residue frequencies, and (2) between two MSA...

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Detalles Bibliográficos
Autores principales: Sadreyev, Ruslan I, Grishin, Nick V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC516024/
https://www.ncbi.nlm.nih.gov/pubmed/15296518
http://dx.doi.org/10.1186/1471-2105-5-106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC516024/
https://www.ncbi.nlm.nih.gov/pubmed/15296518
http://dx.doi.org/10.1186/1471-2105-5-106

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