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Antimicrobial peptide exposure selects for Staphylococcus aureus resistance to human defence peptides

BACKGROUND: The clinical development of antimicrobial peptides (AMPs) is currently under evaluation to combat the rapid increase in MDR bacterial pathogens. However, many AMPs closely resemble components of the human innate immune system and the ramifications of prolonged bacterial exposure to AMPs...

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Detalles Bibliográficos
Autores principales: Kubicek-Sutherland, Jessica Z., Lofton, Hava, Vestergaard, Martin, Hjort, Karin, Ingmer, Hanne, Andersson, Dan I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161045/
https://www.ncbi.nlm.nih.gov/pubmed/27650186
http://dx.doi.org/10.1093/jac/dkw381