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ATG16L1 governs placental infection risk and preterm birth in mice and women

The placenta is a barrier against maternal-fetal transmission of pathogens. Placental infections can cause several adverse pregnancy outcomes, including preterm birth (PTB). Yet, we have limited knowledge regarding the mechanisms the placenta uses to control infections. Here, we show that autophagy,...

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Detalles Bibliográficos
Autores principales: Cao, Bin, Macones, Colin, Mysorekar, Indira U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161251/
https://www.ncbi.nlm.nih.gov/pubmed/28018968
http://dx.doi.org/10.1172/jci.insight.86654