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GADD34 Keeps the mTOR Pathway Inactivated in Endoplasmic Reticulum Stress Related Autophagy

The balance of protein synthesis and proteolysis (i.e. proteostasis) is maintained by a complex regulatory network in which mTOR (mechanistic target of rapamycin serine/threonine kinase) pathway and unfolded protein response are prominent positive and negative actors. The interplay between the two s...

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Detalles Bibliográficos
Autores principales: Holczer, Marianna, Bánhegyi, Gábor, Kapuy, Orsolya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161374/
https://www.ncbi.nlm.nih.gov/pubmed/27992581
http://dx.doi.org/10.1371/journal.pone.0168359