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Isoorientin induces apoptosis, decreases invasiveness, and downregulates VEGF secretion by activating AMPK signaling in pancreatic cancer cells

Isoorientin (or homoorientin) is a flavone, which is a chemical flavonoid-like compound, and a 6-C-glucoside of luteolin. Isoorientin has been demonstrated to have anti-cancer activities against various tumors, but its effects on pancreatic cancer (PC) have not been studied in detail. In this study,...

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Detalles Bibliográficos
Autores principales: Ye, Tingting, Su, Jiadong, Huang, Chaohao, Yu, Dinglai, Dai, Shengjie, Huang, Xince, Chen, Bicheng, Zhou, Mengtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161403/
https://www.ncbi.nlm.nih.gov/pubmed/28003763
http://dx.doi.org/10.2147/OTT.S122653