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Isoorientin induces apoptosis, decreases invasiveness, and downregulates VEGF secretion by activating AMPK signaling in pancreatic cancer cells
Isoorientin (or homoorientin) is a flavone, which is a chemical flavonoid-like compound, and a 6-C-glucoside of luteolin. Isoorientin has been demonstrated to have anti-cancer activities against various tumors, but its effects on pancreatic cancer (PC) have not been studied in detail. In this study,...
Autores principales: | Ye, Tingting, Su, Jiadong, Huang, Chaohao, Yu, Dinglai, Dai, Shengjie, Huang, Xince, Chen, Bicheng, Zhou, Mengtao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161403/ https://www.ncbi.nlm.nih.gov/pubmed/28003763 http://dx.doi.org/10.2147/OTT.S122653 |
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