Targeting DNA Flap Endonuclease 1 to Impede Breast Cancer Progression

DNA flap endonuclease 1 (FEN1) plays critical roles in maintaining genome stability and integrity by participating in both DNA replication and repair. Suppression of FEN1 in cells leads to the retardation of DNA replication and accumulation of unrepaired DNA intermediates, resulting in DNA double st...

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Detalles Bibliográficos
Autores principales: He, Lingfeng, Zhang, Yilan, Sun, Hongfang, Jiang, Feng, Yang, Huan, Wu, Huan, Zhou, Ting, Hu, Sencai, Kathera, Chandra Sekhar, Wang, Xiaojun, Chen, Haoyan, Li, Hongzhi, Shen, Binghui, Zhu, Yongqiang, Guo, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161424/
https://www.ncbi.nlm.nih.gov/pubmed/27852524
http://dx.doi.org/10.1016/j.ebiom.2016.11.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161424/
https://www.ncbi.nlm.nih.gov/pubmed/27852524
http://dx.doi.org/10.1016/j.ebiom.2016.11.012

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