Quantifying β-catenin subcellular dynamics and cyclin D1 mRNA transcription during Wnt signaling in single living cells

Signal propagation from the cell membrane to a promoter can induce gene expression. To examine signal transmission through sub-cellular compartments and its effect on transcription levels in individual cells within a population, we used the Wnt/β-catenin signaling pathway as a model system. Wnt sign...

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Detalles Bibliográficos
Autores principales: Kafri, Pinhas, Hasenson, Sarah E, Kanter, Itamar, Sheinberger, Jonathan, Kinor, Noa, Yunger, Sharon, Shav-Tal, Yaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161448/
https://www.ncbi.nlm.nih.gov/pubmed/27879202
http://dx.doi.org/10.7554/eLife.16748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161448/
https://www.ncbi.nlm.nih.gov/pubmed/27879202
http://dx.doi.org/10.7554/eLife.16748

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