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Quantifying β-catenin subcellular dynamics and cyclin D1 mRNA transcription during Wnt signaling in single living cells

Signal propagation from the cell membrane to a promoter can induce gene expression. To examine signal transmission through sub-cellular compartments and its effect on transcription levels in individual cells within a population, we used the Wnt/β-catenin signaling pathway as a model system. Wnt sign...

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Detalles Bibliográficos
Autores principales:	Kafri, Pinhas, Hasenson, Sarah E, Kanter, Itamar, Sheinberger, Jonathan, Kinor, Noa, Yunger, Sharon, Shav-Tal, Yaron
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161448/ https://www.ncbi.nlm.nih.gov/pubmed/27879202 http://dx.doi.org/10.7554/eLife.16748

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