Successful transmission and transcriptional deployment of a human chromosome via mouse male meiosis

Most human aneuploidies originate maternally, due in part to the presence of highly stringent checkpoints during male meiosis. Indeed, male sterility is common among aneuploid mice used to study chromosomal abnormalities, and male germline transmission of exogenous DNA has been rarely reported. Here...

Descripción completa

Detalles Bibliográficos
Autores principales: Ernst, Christina, Pike, Jeremy, Aitken, Sarah J, Long, Hannah K, Eling, Nils, Stojic, Lovorka, Ward, Michelle C, Connor, Frances, Rayner, Timothy F, Lukk, Margus, Klose, Robert J, Kutter, Claudia, Odom, Duncan T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Genes and Chromosomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161449/
https://www.ncbi.nlm.nih.gov/pubmed/27855777
http://dx.doi.org/10.7554/eLife.20235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161449/
https://www.ncbi.nlm.nih.gov/pubmed/27855777
http://dx.doi.org/10.7554/eLife.20235

Ejemplares similares