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Methylation-Sensitive Melt Curve Analysis of the Reprimo Gene Methylation in Gastric Cancer
Reprimo (RPRM) is a p53-induced tumor suppressor gene. Its aberrant DNA methylation is correlated with carcinogenesis and may be used as a surrogate marker for the early detection of gastric cancer. However, the detail information regarding its DNA methylation has not been revealed. Here, we investi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161478/ https://www.ncbi.nlm.nih.gov/pubmed/27992600 http://dx.doi.org/10.1371/journal.pone.0168635 |