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Methylation-Sensitive Melt Curve Analysis of the Reprimo Gene Methylation in Gastric Cancer

Reprimo (RPRM) is a p53-induced tumor suppressor gene. Its aberrant DNA methylation is correlated with carcinogenesis and may be used as a surrogate marker for the early detection of gastric cancer. However, the detail information regarding its DNA methylation has not been revealed. Here, we investi...

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Detalles Bibliográficos
Autores principales: Wang, Hanze, Zheng, Yansong, Lai, Junzhong, Luo, Qianping, Ke, Huican, Chen, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161478/
https://www.ncbi.nlm.nih.gov/pubmed/27992600
http://dx.doi.org/10.1371/journal.pone.0168635