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Transcriptomic Analysis Shows Decreased Cortical Expression of NR4A1, NR4A2 and RXRB in Schizophrenia and Provides Evidence for Nuclear Receptor Dysregulation

Many genes are differentially expressed in the cortex of people with schizophrenia, implicating factors that control transcription more generally. Hormone nuclear receptors dimerize to coordinate context-dependent changes in gene expression. We hypothesized that members of two families of nuclear re...

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Detalles Bibliográficos
Autores principales: Corley, Susan M., Tsai, Shan-Yuan, Wilkins, Marc R., Shannon Weickert, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161508/
https://www.ncbi.nlm.nih.gov/pubmed/27992436
http://dx.doi.org/10.1371/journal.pone.0166944