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CITED2 Cooperates with ISL1 and Promotes Cardiac Differentiation of Mouse Embryonic Stem Cells

The transcriptional regulator CITED2 is essential for heart development. Here, we investigated the role of CITED2 in the specification of cardiac cell fate from mouse embryonic stem cells (ESC). The overexpression of CITED2 in undifferentiated ESC was sufficient to promote cardiac cell emergence upo...

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Detalles Bibliográficos
Autores principales: Pacheco-Leyva, Ivette, Matias, Ana Catarina, Oliveira, Daniel V., Santos, João M.A., Nascimento, Rita, Guerreiro, Eduarda, Michell, Anna C., van De Vrugt, Annebel M., Machado-Oliveira, Gisela, Ferreira, Guilherme, Domian, Ibrahim, Bragança, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161512/
https://www.ncbi.nlm.nih.gov/pubmed/27818139
http://dx.doi.org/10.1016/j.stemcr.2016.10.002