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CITED2 Cooperates with ISL1 and Promotes Cardiac Differentiation of Mouse Embryonic Stem Cells
The transcriptional regulator CITED2 is essential for heart development. Here, we investigated the role of CITED2 in the specification of cardiac cell fate from mouse embryonic stem cells (ESC). The overexpression of CITED2 in undifferentiated ESC was sufficient to promote cardiac cell emergence upo...
Autores principales: | Pacheco-Leyva, Ivette, Matias, Ana Catarina, Oliveira, Daniel V., Santos, João M.A., Nascimento, Rita, Guerreiro, Eduarda, Michell, Anna C., van De Vrugt, Annebel M., Machado-Oliveira, Gisela, Ferreira, Guilherme, Domian, Ibrahim, Bragança, José |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161512/ https://www.ncbi.nlm.nih.gov/pubmed/27818139 http://dx.doi.org/10.1016/j.stemcr.2016.10.002 |
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