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High glucose repatterns human podocyte energy metabolism during differentiation and diabetic nephropathy

Podocytes play a key role in diabetic nephropathy pathogenesis, but alteration of their metabolism remains unknown in human kidney. By using a conditionally differentiating human podocyte cell line, we addressed the functional and molecular changes in podocyte energetics during in vitro development...

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Detalles Bibliográficos
Autores principales: Imasawa, Toshiyuki, Obre, Emilie, Bellance, Nadège, Lavie, Julie, Imasawa, Tomoko, Rigothier, Claire, Delmas, Yahsou, Combe, Christian, Lacombe, Didier, Benard, Giovanni, Claverol, Stéphane, Bonneu, Marc, Rossignol, Rodrigue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161522/
https://www.ncbi.nlm.nih.gov/pubmed/27825100
http://dx.doi.org/10.1096/fj.201600293R