A reverse genetics cell-based evaluation of genes linked to healthy human tissue age

We recently developed a binary (i.e., young vs. old) classifier using human muscle RNA profiles that accurately distinguished the age of multiple tissue types. Pathway analysis did not reveal regulators of these 150 genes, so we used reverse genetics and pharmacologic methods to explore regulation o...

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Detalles Bibliográficos
Autores principales: Crossland, Hannah, Atherton, Philip J., Strömberg, Anna, Gustafsson, Thomas, Timmons, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161526/
https://www.ncbi.nlm.nih.gov/pubmed/27698205
http://dx.doi.org/10.1096/fj.201600296RRR

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161526/
https://www.ncbi.nlm.nih.gov/pubmed/27698205
http://dx.doi.org/10.1096/fj.201600296RRR

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