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Oxidative diversification of amino acids and peptides by small-molecule iron catalysis
Secondary metabolites synthesized by nonribosomal peptide synthetases (NRPSs) display diverse and complex topologies and possess an impressive range of biological activities(1,2) Much of this diversity derives from a synthetic strategy that entails the oxidation of both the chiral amino acid buildin...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161617/ https://www.ncbi.nlm.nih.gov/pubmed/27479323 http://dx.doi.org/10.1038/nature18941 |