Cargando…
Oxidative diversification of amino acids and peptides by small-molecule iron catalysis
Secondary metabolites synthesized by nonribosomal peptide synthetases (NRPSs) display diverse and complex topologies and possess an impressive range of biological activities(1,2) Much of this diversity derives from a synthetic strategy that entails the oxidation of both the chiral amino acid buildin...
Autores principales: | Osberger, Thomas J., Rogness, Donald C., Kohrt, Jeffrey T., Stepan, Antonia F., White, M. Christina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161617/ https://www.ncbi.nlm.nih.gov/pubmed/27479323 http://dx.doi.org/10.1038/nature18941 |
Ejemplares similares
-
N-Boc Amines to Oxazolidinones
via Pd(II)/Bis-sulfoxide/Brønsted Acid Co-Catalyzed Allylic C–H
Oxidation
por: Osberger, Thomas J., et al.
Publicado: (2014) -
Small peptide diversification through photoredox-catalyzed oxidative C-terminal modification
por: Le Du, Eliott, et al.
Publicado: (2021) -
Simulations to Cover the Waterfront for Iron Oxide Catalysis
por: Snir, Nadav, et al.
Publicado: (2022) -
Chemical Modification of Dehydrated Amino Acids in Natural Antimicrobial Peptides by Photoredox Catalysis
por: de Bruijn, A. Dowine, et al.
Publicado: (2018) -
Prospects of In vivo Incorporation of Non-canonical Amino Acids for the Chemical Diversification of Antimicrobial Peptides
por: Baumann, Tobias, et al.
Publicado: (2017)