Ubiquitin Utilizes an Acidic Surface Patch to Alter Chromatin Structure

Ubiquitylation of histone H2B, associated with gene activation, leads to chromatin decompaction through an unknown mechanism. We used a hydrogen-deuterium exchange strategy coupled with nuclear magnetic resonance spectroscopy to map the ubiquitin surface responsible for its structural effects on chr...

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Detalles Bibliográficos
Autores principales: Debelouchina, Galia T., Gerecht, Karola, Muir, Tom W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161692/
https://www.ncbi.nlm.nih.gov/pubmed/27870837
http://dx.doi.org/10.1038/nchembio.2235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161692/
https://www.ncbi.nlm.nih.gov/pubmed/27870837
http://dx.doi.org/10.1038/nchembio.2235

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