Cargando…

Structural basis for the antifolding activity of a molecular chaperone

Molecular chaperones act on non-native proteins in the cell to prevent their aggregation, premature folding or misfolding. Different chaperones often exert distinct effects, such as acceleration or delay of folding, on client proteins via mechanisms that are poorly understood. Here we report the sol...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Chengdong, Rossi, Paolo, Saio, Tomohide, Kalodimos, Charalampos G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161705/
https://www.ncbi.nlm.nih.gov/pubmed/27501151
http://dx.doi.org/10.1038/nature18965