Identification of G-quadruplexes in long functional RNAs using 7-deaza-Guanine RNA

RNA G-quadruplex (G4) structures are thought to affect biological processes, including translation and pre-mRNA splicing, but it is not possible at present to demonstrate that they form naturally at specific sequences within long functional RNA molecules. We have developed a novel strategy, footprin...

Descripción completa

Detalles Bibliográficos
Autores principales: Weldon, Carika, Behm-Ansmant, Isabelle, Hurley, Laurence H., Burley, Glenn A., Branlant, Christiane, Eperon, Ian C., Dominguez, Cyril
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5164935/
https://www.ncbi.nlm.nih.gov/pubmed/27820800
http://dx.doi.org/10.1038/nchembio.2228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5164935/
https://www.ncbi.nlm.nih.gov/pubmed/27820800
http://dx.doi.org/10.1038/nchembio.2228

Ejemplares similares