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Identification of G-quadruplexes in long functional RNAs using 7-deaza-Guanine RNA
RNA G-quadruplex (G4) structures are thought to affect biological processes, including translation and pre-mRNA splicing, but it is not possible at present to demonstrate that they form naturally at specific sequences within long functional RNA molecules. We have developed a novel strategy, footprin...
Autores principales: | Weldon, Carika, Behm-Ansmant, Isabelle, Hurley, Laurence H., Burley, Glenn A., Branlant, Christiane, Eperon, Ian C., Dominguez, Cyril |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5164935/ https://www.ncbi.nlm.nih.gov/pubmed/27820800 http://dx.doi.org/10.1038/nchembio.2228 |
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