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Decreased S100A9 Expression Promoted Rat Airway Smooth Muscle Cell Proliferation by Stimulating ROS Generation and Inhibiting p38 MAPK

Background. Asthma is a disease with a core abnormality in airway smooth muscle function, and the proliferation of airway smooth muscle cells (ASMCs) plays a pivotal role in asthma airway remodeling. Our previous study showed that S100A9 (S100 calcium-binding protein A9; 400 and 800 ng/mL) significa...

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Detalles Bibliográficos
Autores principales: Yin, Lei-Miao, Han, Xiao-Jie, Duan, Ting-Ting, Xu, Yu-Dong, Wang, Yu, Ulloa, Luis, Yang, Yong-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165165/
https://www.ncbi.nlm.nih.gov/pubmed/28050155
http://dx.doi.org/10.1155/2016/1462563