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Broadly Neutralizing Antibodies Display Potential for Prevention of HIV-1 Infection of Mucosal Tissue Superior to That of Nonneutralizing Antibodies

Definition of the key parameters mediating effective antibody blocking of HIV-1 acquisition within mucosal tissue may prove critical to effective vaccine development and the prophylactic use of monoclonal antibodies. Although direct antibody-mediated neutralization is highly effective against cell-f...

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Detalles Bibliográficos
Autores principales: Cheeseman, Hannah M., Olejniczak, Natalia J., Rogers, Paul M., Evans, Abbey B., King, Deborah F. L., Ziprin, Paul, Liao, Hua-Xin, Haynes, Barton F., Shattock, Robin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165208/
https://www.ncbi.nlm.nih.gov/pubmed/27795431
http://dx.doi.org/10.1128/JVI.01762-16