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CLEC5A-Mediated Enhancement of the Inflammatory Response in Myeloid Cells Contributes to Influenza Virus Pathogenicity In Vivo

Human infections with influenza viruses exhibit mild to severe clinical outcomes as a result of complex virus-host interactions. Induction of inflammatory mediators via pattern recognition receptors may dictate subsequent host responses for pathogen clearance and tissue damage. We identified that hu...

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Detalles Bibliográficos
Autores principales: Teng, Ooiean, Chen, Szu-Ting, Hsu, Tsui-Ling, Sia, Sin Fun, Cole, Suzanne, Valkenburg, Sophie A., Hsu, Tzu-Yun, Zheng, Jian Teddy, Tu, Wenwei, Bruzzone, Roberto, Peiris, Joseph Sriyal Malik, Hsieh, Shie-Liang, Yen, Hui-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165214/
https://www.ncbi.nlm.nih.gov/pubmed/27795434
http://dx.doi.org/10.1128/JVI.01813-16