A Bioequivalence Test by the Direct Comparison of Concentration-versus-Time Curves Using Local Polynomial Smoothers

In order to test if two chemically or pharmaceutically equivalent products have the same efficacy and/or toxicity, a bioequivalence (BE) study is conducted. The 80%/125% rule is the most commonly used criteria for BE and states that BE cannot be claimed unless the 90% CIs for the ratio of selected p...

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Detalles Bibliográficos
Autores principales: Tian, Suyan, Chang, Howard H., Orange, Dana, Gu, Jingkai, Suárez-Fariñas, Mayte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165228/
https://www.ncbi.nlm.nih.gov/pubmed/28050196
http://dx.doi.org/10.1155/2016/4680642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165228/
https://www.ncbi.nlm.nih.gov/pubmed/28050196
http://dx.doi.org/10.1155/2016/4680642

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