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Cellular Prion Protein (PrP(c)) and Hypoxia: True to Each Other in Good Times and in Bad, in Sickness, and in Health

The cellular prion protein (PrP(c)) and hypoxia appear to be tightly intertwined. Beneficial effects of PrP(c) on neuronal survival under hypoxic conditions such as focal cerebral ischemia are strongly supported. Conversely, increasing evidence indicates detrimental effects of increased PrP(c) expre...

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Detalles Bibliográficos
Autores principales: Ramljak, Sanja, Herlyn, Holger, Zerr, Inga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165248/
https://www.ncbi.nlm.nih.gov/pubmed/28066187
http://dx.doi.org/10.3389/fncel.2016.00292