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Coxiella burnetii Employs the Dot/Icm Type IV Secretion System to Modulate Host NF-κB/RelA Activation

Coxiella burnetii is the causative agent of Q fever and an obligate intracellular pathogen in nature that survives and grows in a parasitophorous vacuole (PV) within eukaryotic host cells. C. burnetii promotes intracellular survival by subverting apoptotic and pro-inflammatory signaling pathways tha...

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Detalles Bibliográficos
Autores principales: Mahapatra, Saugata, Gallaher, Brandi, Smith, Sydni Caet, Graham, Joseph G., Voth, Daniel E., Shaw, Edward I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165255/
https://www.ncbi.nlm.nih.gov/pubmed/28066723
http://dx.doi.org/10.3389/fcimb.2016.00188