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Coxiella burnetii Employs the Dot/Icm Type IV Secretion System to Modulate Host NF-κB/RelA Activation
Coxiella burnetii is the causative agent of Q fever and an obligate intracellular pathogen in nature that survives and grows in a parasitophorous vacuole (PV) within eukaryotic host cells. C. burnetii promotes intracellular survival by subverting apoptotic and pro-inflammatory signaling pathways tha...
Autores principales: | Mahapatra, Saugata, Gallaher, Brandi, Smith, Sydni Caet, Graham, Joseph G., Voth, Daniel E., Shaw, Edward I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165255/ https://www.ncbi.nlm.nih.gov/pubmed/28066723 http://dx.doi.org/10.3389/fcimb.2016.00188 |
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