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In Silico Study of Alkaloids as α-Glucosidase Inhibitors: Hope for the Discovery of Effective Lead Compounds

α-Glucosidase (extinction coefficient 3.2.1.20) is a primary carbohydrate metabolizing enzyme that acts on the 1–4 associated α-glucose residues. The inhibition of α-glucosidase slows down the process of carbohydrate digestion and avoids postprandial hyperglycemia, which is a major cause of chronic...

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Detalles Bibliográficos
Autores principales: Zafar, Muhammad, Khan, Haroon, Rauf, Abdur, Khan, Ajmal, Lodhi, Muhammad Arif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165266/
https://www.ncbi.nlm.nih.gov/pubmed/28066324
http://dx.doi.org/10.3389/fendo.2016.00153