Prediction of Differentiation Tendency Toward Hepatocytes from Gene Expression in Undifferentiated Human Pluripotent Stem Cells

Functional hepatocytes derived from human pluripotent stem cells (hPSCs) have potential as tools for predicting drug-induced hepatotoxicity in the early phases of drug development. However, the propensity of hPSC lines to differentiate into specific lineages is reported to differ. The ability to pre...

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Detalles Bibliográficos
Autores principales: Yanagihara, Kana, Liu, Yujung, Kanie, Kei, Takayama, Kazuo, Kokunugi, Minako, Hirata, Mitsuhi, Fukuda, Takayuki, Suga, Mika, Nikawa, Hiroki, Mizuguchi, Hiroyuki, Kato, Ryuji, Furue, Miho K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Original Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165660/
https://www.ncbi.nlm.nih.gov/pubmed/27733097
http://dx.doi.org/10.1089/scd.2016.0099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165660/
https://www.ncbi.nlm.nih.gov/pubmed/27733097
http://dx.doi.org/10.1089/scd.2016.0099

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