CREM Alpha Enhances IL-21 Production in T Cells In Vivo and In Vitro

The cAMP-responsive element modulator alpha (CREMα) plays a role in autoimmunity and, in particular, in systemic lupus erythematosus. CREMα negatively regulates IL-2 transcription and activates IL-17 expression by direct transcriptional mechanisms. To understand the role of CREM in autoimmunity, we...

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Detalles Bibliográficos
Autores principales: Ohl, Kim, Wiener, Anastasia, Lippe, Ralph, Schippers, Angela, Zorn, Carolin, Roth, Johannes, Wagner, Norbert, Tenbrock, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165720/
https://www.ncbi.nlm.nih.gov/pubmed/28066428
http://dx.doi.org/10.3389/fimmu.2016.00618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165720/
https://www.ncbi.nlm.nih.gov/pubmed/28066428
http://dx.doi.org/10.3389/fimmu.2016.00618

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