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LIS1 Regulates Osteoclastogenesis through Modulation of M-SCF and RANKL Signaling Pathways and CDC42

We have previously reported that depletion of LIS1, a key regulator of microtubules and cytoplasmic dynein motor complex, in osteoclast precursor cells by shRNAs attenuates osteoclastogenesis in vitro. However, the underlying mechanisms remain unclear. In this study, we show that conditional deletio...

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Detalles Bibliográficos
Autores principales: Ye, Shiqiao, Fujiwara, Toshifumi, Zhou, Jian, Varughese, Kottayil I, Zhao, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166490/
https://www.ncbi.nlm.nih.gov/pubmed/27994513
http://dx.doi.org/10.7150/ijbs.15583