NK cells converge lytic granules to promote cytotoxicity and prevent bystander killing

Natural killer (NK) cell activation triggers sequential cellular events leading to destruction of diseased cells. We previously identified lytic granule convergence, a dynein- and integrin signal–dependent movement of lysosome-related organelles to the microtubule-organizing center, as an early step...

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Detalles Bibliográficos
Autores principales: Hsu, Hsiang-Ting, Mace, Emily M., Carisey, Alexandre F., Viswanath, Dixita I., Christakou, Athanasia E., Wiklund, Martin, Önfelt, Björn, Orange, Jordan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166499/
https://www.ncbi.nlm.nih.gov/pubmed/27903610
http://dx.doi.org/10.1083/jcb.201604136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166499/
https://www.ncbi.nlm.nih.gov/pubmed/27903610
http://dx.doi.org/10.1083/jcb.201604136

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