Atg8 family LC3/GABARAP proteins are crucial for autophagosome–lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation

Members of the Atg8 family of proteins are conjugated to autophagosomal membranes, where they have been proposed to drive autophagosome formation and selective sequestration of cargo. In mammals, the Atg8 family consists of six members divided into the LC3 and GABARAP subfamilies. To define Atg8 fun...

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Detalles Bibliográficos
Autores principales: Nguyen, Thanh Ngoc, Padman, Benjamin Scott, Usher, Joanne, Oorschot, Viola, Ramm, Georg, Lazarou, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166504/
https://www.ncbi.nlm.nih.gov/pubmed/27864321
http://dx.doi.org/10.1083/jcb.201607039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166504/
https://www.ncbi.nlm.nih.gov/pubmed/27864321
http://dx.doi.org/10.1083/jcb.201607039

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