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Natural killer cell granules converge to avoid collateral damage

To clear infection, cytotoxic lymphocytes must destroy target cells while avoiding nonspecific killing of surrounding healthy cells. In this issue, Hsu et al. (2016. J. Cell Biol. https://doi.org/10.1083/jcb.201604136) use live-cell imaging to show that lytic granule convergence protects bystander c...

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Detalles Bibliográficos
Autores principales: Ritter, Alex T., Mellman, Ira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166509/
https://www.ncbi.nlm.nih.gov/pubmed/27932575
http://dx.doi.org/10.1083/jcb.201612003