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An Intact Kidney Slice Model to Investigate Vasa Recta Properties and Function in situ

BACKGROUND: Medullary blood flow is via vasa recta capillaries, which possess contractile pericytes. In vitro studies using isolated descending vasa recta show that pericytes can constrict/dilate descending vasa recta when vasoactive substances are present. We describe a live kidney slice model in w...

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Detalles Bibliográficos
Autores principales: Crawford, C., Kennedy-Lydon, T., Sprott, C., Desai, T., Sawbridge, L., Munday, J., Unwin, R.J., Wildman, S.S.P., Peppiatt-Wildman, C.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166522/
https://www.ncbi.nlm.nih.gov/pubmed/22833057
http://dx.doi.org/10.1159/000339110