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Brown Seaweed Fucoidan Inhibits Cancer Progression by Dual Regulation of mir-29c/ADAM12 and miR-17-5p/PTEN Axes in Human Breast Cancer Cells

In this study, we observed that brown seaweed fucoidan inhibited human breast cancer progression by upregulating microRNA (miR)-29c and downregulating miR-17-5p, thereby suppressing their target genes, a disintegrin and metalloproteinase 12 (ADAM12) and phosphatase and tensin homolog (PTEN), respect...

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Detalles Bibliográficos
Autores principales: Wu, Szu-Yuan, Yan, Ming-De, Wu, Alexander T.H., Yuan, Kevin Sheng-Po, Liu, Shing Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166552/
https://www.ncbi.nlm.nih.gov/pubmed/27994679
http://dx.doi.org/10.7150/jca.15703