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Modeling of the mechano-chemical behaviour of the nuclear pore complex: current research and perspectives

Recent evidence suggests that mechanical deformation of the cell nucleus regulates the nuclear import of the transcriptional activators of genes involved in primary physiological cell responses such as stem cell differentiation. In addition, this nuclear mechanosensing response is de-regulated in pa...

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Detalles Bibliográficos
Autores principales: Garcia, Alberto, Rodriguez Matas, Jose F., Raimondi, Manuela T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166569/
https://www.ncbi.nlm.nih.gov/pubmed/27713975
http://dx.doi.org/10.1039/c6ib00153j