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Assembly-based inference of B-cell receptor repertoires from short read RNA sequencing data with V’DJer

Motivation: B-cell receptor (BCR) repertoire profiling is an important tool for understanding the biology of diverse immunologic processes. Current methods for analyzing adaptive immune receptor repertoires depend upon PCR amplification of VDJ rearrangements followed by long read amplicon sequencing...

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Detalles Bibliográficos
Autores principales: Mose, Lisle E., Selitsky, Sara R., Bixby, Lisa M., Marron, David L., Iglesia, Michael D., Serody, Jonathan S., Perou, Charles M., Vincent, Benjamin G., Parker, Joel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167060/
https://www.ncbi.nlm.nih.gov/pubmed/27559159
http://dx.doi.org/10.1093/bioinformatics/btw526