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Assembly-based inference of B-cell receptor repertoires from short read RNA sequencing data with V’DJer
Motivation: B-cell receptor (BCR) repertoire profiling is an important tool for understanding the biology of diverse immunologic processes. Current methods for analyzing adaptive immune receptor repertoires depend upon PCR amplification of VDJ rearrangements followed by long read amplicon sequencing...
Autores principales: | Mose, Lisle E., Selitsky, Sara R., Bixby, Lisa M., Marron, David L., Iglesia, Michael D., Serody, Jonathan S., Perou, Charles M., Vincent, Benjamin G., Parker, Joel S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167060/ https://www.ncbi.nlm.nih.gov/pubmed/27559159 http://dx.doi.org/10.1093/bioinformatics/btw526 |
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