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STAMS: STRING-assisted module search for genome wide association studies and application to autism

Motivation: Analyzing genome wide association data in the context of biological pathways helps us understand how genetic variation influences phenotype and increases power to find associations. However, the utility of pathway-based analysis tools is hampered by undercuration and reliance on a distri...

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Detalles Bibliográficos
Autores principales: Hillenmeyer, Sara, Davis, Lea K., Gamazon, Eric R., Cook, Edwin H., Cox, Nancy J., Altman, Russ B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167061/
https://www.ncbi.nlm.nih.gov/pubmed/27542772
http://dx.doi.org/10.1093/bioinformatics/btw530