Cargando…

Tertiary Epimutations – A Novel Aspect of Epigenetic Transgenerational Inheritance Promoting Genome Instability

Exposure to environmental factors can induce the epigenetic transgenerational inheritance of disease. Alterations to the epigenome termed “epimutations” include “primary epimutations” which are epigenetic alterations in the absence of genetic change and “secondary epimutations” which form following...

Descripción completa

Detalles Bibliográficos
Autores principales: McCarrey, John R., Lehle, Jake D., Raju, Seetha S., Wang, Yufeng, Nilsson, Eric E., Skinner, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167269/
https://www.ncbi.nlm.nih.gov/pubmed/27992467
http://dx.doi.org/10.1371/journal.pone.0168038