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Alternative lengthening of human telomeres is a conservative DNA replication process with features of break‐induced replication

Human malignancies overcome replicative senescence either by activating the reverse‐transcriptase telomerase or by utilizing a homologous recombination‐based mechanism, referred to as alternative lengthening of telomeres (ALT). In budding yeast, ALT exhibits features of break‐induced replication (BI...

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Detalles Bibliográficos
Autores principales: Roumelioti, Fani‐Marlen, Sotiriou, Sotirios K, Katsini, Vasiliki, Chiourea, Maria, Halazonetis, Thanos D, Gagos, Sarantis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167343/
https://www.ncbi.nlm.nih.gov/pubmed/27760777
http://dx.doi.org/10.15252/embr.201643169