Inactivation of the type I interferon pathway reveals long double‐stranded RNA‐mediated RNA interference in mammalian cells

RNA interference (RNAi) elicited by long double‐stranded (ds) or base‐paired viral RNA constitutes the major mechanism of antiviral defence in plants and invertebrates. In contrast, it is controversial whether it acts in chordates. Rather, in vertebrates, viral RNAs induce a distinct defence system...

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Detalles Bibliográficos
Autores principales: Maillard, Pierre V, Van der Veen, Annemarthe G, Deddouche‐Grass, Safia, Rogers, Neil C, Merits, Andres, Reis e Sousa, Caetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167344/
https://www.ncbi.nlm.nih.gov/pubmed/27815315
http://dx.doi.org/10.15252/embj.201695086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167344/
https://www.ncbi.nlm.nih.gov/pubmed/27815315
http://dx.doi.org/10.15252/embj.201695086

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