Seipin regulates ER–lipid droplet contacts and cargo delivery

Seipin is an endoplasmic reticulum (ER) membrane protein implicated in lipid droplet (LD) biogenesis and mutated in severe congenital lipodystrophy (BSCL2). Here, we show that seipin is stably associated with nascent ER–LD contacts in human cells, typically via one mobile focal point per LD. Seipin...

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Detalles Bibliográficos
Autores principales: Salo, Veijo T, Belevich, Ilya, Li, Shiqian, Karhinen, Leena, Vihinen, Helena, Vigouroux, Corinne, Magré, Jocelyne, Thiele, Christoph, Hölttä‐Vuori, Maarit, Jokitalo, Eija, Ikonen, Elina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167346/
https://www.ncbi.nlm.nih.gov/pubmed/27879284
http://dx.doi.org/10.15252/embj.201695170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167346/
https://www.ncbi.nlm.nih.gov/pubmed/27879284
http://dx.doi.org/10.15252/embj.201695170

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