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RhoA Proteolysis Regulates the Actin Cytoskeleton in Response to Oxidative Stress

The small GTPase RhoA regulates the actin cytoskeleton to affect multiple cellular processes including endocytosis, migration and adhesion. RhoA activity is tightly regulated through several mechanisms including GDP/GTP cycling, phosphorylation, glycosylation and prenylation. Previous reports have a...

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Detalles Bibliográficos
Autores principales: Girouard, Marie-Pier, Pool, Madeline, Alchini, Ricardo, Rambaldi, Isabel, Fournier, Alyson E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167403/
https://www.ncbi.nlm.nih.gov/pubmed/27992599
http://dx.doi.org/10.1371/journal.pone.0168641